What does nasopharyngeal cancer rely on for cancer cell clearance after 33 rounds of radiotherapy and 4 rounds of chemotherapy?

1. Nasal congestion

This is the symptom most easily confused with rhinitis. Nasal congestion caused by rhinitis can usually be alleviated through medication. However, many symptoms of nasopharyngeal cancer, although somewhat similar to those of rhinitis, are generally not responsive to treatment with medication. If long-term nasal congestion occurs, it is recommended to seek medical attention.

       

2. Blood in nasal mucus

A typical early symptom of nasopharyngeal cancer is the presence of blood streaks or clumps in nasal mucus when forcefully inhaling from the nose, especially upon waking up in the morning.

       

3. Painless enlargement of cervical lymph nodes

In patients with nasopharyngeal carcinoma, approximately 60%～80% initially present with cervical masses^[3], usually in the retroauricular and upper cervical regions.

       

4. Headache

Headaches caused by early nasopharyngeal cancer are usually intermittent, often located on one side of the temporal, parietal, or occipital regions, and manifest as throbbing or sharp pain. Such headaches may be related to tumor invasion of the skull base or cranial nerves. As the disease progresses, the headache may gradually worsen, even becoming persistent, and symptoms may be more pronounced at night.

       

5. Hearing problems

may be ear congestion, tinnitus, or hearing loss. When the tumor blocks the eustachian tube opening, tinnitus and ear congestion appear, and further progression leads to hearing loss. At this time, it must not be misdiagnosed as an ear disease.

Looking back and comparing with Mr. Zhao's earliest symptoms, 5of the major symptoms match with 3items. It is important to pay attention to the differentiation of early symptoms, as health is not trivial.

       

Remember to share the life-saving knowledge with your family and friends ~ and forward it

[1]Long Z, Wang W, Liu W, et al. Trend of nasopharyngeal carcinoma mortality and years of life lost in China and its provinces from 2005 to 2020. Int J Cancer. 2022; 151(5):684-691.

[2]Miao Xu, Youyuan Yao, Jianjun Liu, et.al. Genome sequencing analysis identifies Epstein–Barr virus subtypes associated with high risk of nasopharyngeal carcinoma. Nature Genetics 17 June 2019

[3]Zhang Zengxiao, Jiang Jiaxin, Jiang Yan. The pattern of nasopharyngeal carcinoma invading and developing around [J]. Chinese Journal of Otorhinolaryngology Head and Neck Surgery, 2022, 57(11) : 1378-1383.

[4]He Meilin,Yi Junlin.Current status of treatment for recurrent nasopharyngeal carcinoma[J].Chinese Journal of Radiation Oncology, 2021, 30(11):1202-1208.

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Written by Zhang Tuo      

Reviewed by: Qiao Jiacheng, Wang Ying, Gao Chen      

Edited/typeset by Zhang Jiao